Antiage Therapy consists of a series of treatments that try to adjust biological markers to enhance health and extend life.
Due to the demographic evolution in the world, the need for therapies that help to optimize aging have emerged. Their main objective is to improve the quality of people’s lives. This type of medicine is known as Antiage Therapy.
Recent scientific advances are helping us understand the aging process, and have given birth to antiaging medicine. This is based on measures that slow down, stop and even reverse the effects of aging, as well as increase life expectancy.
There are different medical-nutritional interventions, and in this article I will explore the main ones.
Of all the measures studied, caloric restriction, i.e., reducing the amount of energy we consume (without creating a nutritional deficit), is the one that shows the greatest potential. (1,2). Among the benefits attributed to this nutritional intervention are protection against obesity, cardiovascular disease, hypertension, and cancer (3).
Aging reduces the ability to produce hormones, and low hormone levels are associated with skin changes, decreased muscle mass, bone density, and mood swings. Aging also influences intellectual activity, sexual desire, and sexual potential (4,5,6).
Testosterone replacement therapy increases muscle and bone mass, as well as strength (7). It also supports various cognitive functions like language, spatial ability, and memory (8). In menopausal women, DHEA therapy appears to be very beneficial. These therapies can have adverse effects like polycythemia (increased hemoglobin and red blood cells), venous thrombosis, and prostate cancer.
This kind of intervention’s contraindications include: suspected prostate cancer, having severe urinary symptoms, elevated hemoglobin, coronary artery disease, uncontrolled heart failure, and untreated sleep apnea (8).
The intestinal microbiota (set of micro-organisms present in the intestine) needs to be considered. Its role in regulating health and life expectancy has been proven (9). Specifically, the intestinal microbiota is important when it comes to resisting infections, inflammation, autoimmunity, and cancer. It regulates the brain-intestine axis (10). Therefore, combining nutritional intervention with supplements that improve the intestinal microbiota is advantageous in Antiage Therapy.
Vitamin D plays an important role in metabolizing calcium. Its deficiency has been linked to cognitive decline and Alzheimer’s, loss of muscle mass, osteoporosis, as well as heart problems like heart failure and coronary artery disease (11, 12, 13, 14). A recent study on vitamin D reported anticancer effects, and that it inhibited the growth of different types of cancer (15). In this context, several scientific organizations have developed recommendations to perform vitamin D therapy. I know that vitamin D will be the main source of antiaging medicine in the near future, due to its numerous beneficial effects on the elderly population.
In this care, the patient’s condition, expectations, and objectives are assessed to decide what type (s) of Antiage Therapy can be applied in each particular case.
Ready to slow down the passage of time? In order to get started, you must complete an initial evaluation in which I take your medical history, conduct a physical-anthropometric examination, and then define what type (s) of therapy would benefit you most.
This includes the initial appointment and formulation of an anti-aging plan: nutrition, medicine, hormonal supplementation, intravenous therapies, exercise, & etc.
* Does not include recommended products.
- Speakman JR, Mitchell SE. Caloric restriction. Mol Aspects Med. 2011;32:159–221.
- Masoro EJ. Overview of caloric restriction and ageing. Mech Ageing Dev. 2005;126:913–22.
- Al-Regaiey KA. The effects of calorie restriction on aging: a brief review. Eur Rev Med Pharmacol Sci. 2016;20:2468–73.
- Samaras N, Samaras D, Lang PO, Forster A, Pichard C, Frangos E, et al. A view of geriatrics through hormones: what is the relation between andropause and well-known geriatric syndromes? Maturitas. 2013;74:213–9.
- Sim MY, Kim SH, Kim KM. Seasonal variations and correlations between vitamin D and total testosterone levels. Korean J Fam Med. 2017;38:270–5.
- Emmelot-Vonk MH, Verhaar HJ, Nakhai Pour HR, Aleman A, Lock TM, Bosch JL, et al. Effect of testosterone supplementation on functional mobility, cognition, and other parameters in older men: a randomized controlled trial. JAMA. 2008;299:39–52.
- Kenny AM, Kleppinger A, Annis K, Rathier M, Browner B, Judge JO, et al. Effects of transdermal testosterone on bone and muscle in older men with low bioavailable testosterone levels, low bone mass, and physical frailty. J Am Geriatr Soc. 2010;58:1134–43.
- Samaras N, Papadopoulou MA, Samaras D, Ongaro F. Off-label use of hormones as an antiaging strategy: a review. Clin Interv Aging. 2014;9:1175–86.
- Binstock RH. Anti-aging medicine and research: a realm of conflict and profound societal implications. J Gerontol A Biol Sci Med Sci. 2004;59:B523–33
- Konturek PC, Haziri D, Brzozowski T, Hess T, Heyman S, Kwiecien S, et al. Emerging role of fecal microbiota therapy in the treatment of gastrointestinal and extra-gastrointestinal diseases. J Physiol Pharmacol. 2015;66:483–91.
- Balion C, Griffith LE, Strifler L, Henderson M, Patterson C, Heckman G, et al. Vitamin D, cognition, and dementia: a systematic review and meta-analysis. Neurology. 2012;79:1397–405.
- Janssen HC, Samson MM, Verhaar HJ. Vitamin D deficiency, muscle function, and falls in elderly people. Am J Clin Nutr. 2002;75:611–5.
- Douglas AS, Dunnigan MG, Allan TM, Rawles JM. Seasonal variation in coronary heart disease in Scotland. J Epidemiol Community Health. 1995;49:575–82.
- Rostand SG. Ultraviolet light may contribute to geographic and racial blood pressure differences. Hypertension. 1997;30(2 Pt 1):150–6.
- Deeb KK, Trump DL, Johnson CS. Vitamin D signalling pathways in cancer: potential for anticancer therapeutics. Nat Rev Cancer. 2007;7:684–700.